Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 478
Gene Symbol: ATP1A3
ATP1A3 		0.010 Biomarker disease BEFREE Whereas ATP1A3 is a replicated gene in rare neuropediatric diseases, this gene has previously been linked with COS in only one case report. 29895895 2018
Entrez Id: 23040
Gene Symbol: MYT1L
MYT1L 		0.310 Biomarker disease PSYGENET We previously reported two patients with COS who carried a microduplication disrupting the PXDN and MYT1L genes at 2p25.3. 22547139 2012
Entrez Id: 23040
Gene Symbol: MYT1L
MYT1L 		0.310 GeneticVariation disease BEFREE We previously reported two patients with COS who carried a microduplication disrupting the PXDN and MYT1L genes at 2p25.3. 22547139 2012
Entrez Id: 7837
Gene Symbol: PXDN
PXDN 		0.010 GeneticVariation disease BEFREE We previously reported two patients with COS who carried a microduplication disrupting the PXDN and MYT1L genes at 2p25.3. 22547139 2012
Entrez Id: 2571
Gene Symbol: GAD1
GAD1 		0.020 Biomarker disease BEFREE Thus, it is of interest to examine the association of GAD1 to child BP-I because of its recently reported association to childhood SZ. 18294085 2008
Entrez Id: 1139
Gene Symbol: CHRNA7
CHRNA7 		0.010 GeneticVariation disease BEFREE This study documents that the 15q13.3 deletion and duplication exhibit pathogenicity for COS, with both copy number variants (CNVs) sharing a disrupted CHRNA7 gene. 26968334 2016
Entrez Id: 124590
Gene Symbol: USH1G
USH1G 		0.010 Biomarker disease BEFREE Scores from the Scales for the Assessment of Positive and Negative Symptoms (SAPS & SANS) from 125 COS patients were assessed for fit with previously established symptom dimensions from AOS literature using confirmatory factor analysis (CFA). 29146021 2018
Entrez Id: 26585
Gene Symbol: GREM1
GREM1 		0.010 AlteredExpression disease BEFREE Negative regulators of the bone morphogenetic protein (BMP) pathway were upregulated in SCZ GPCs, including BAMBI, FST, and GREM1, whose overexpression retained SCZ GPCs at the progenitor stage. 31242417 2019
Entrez Id: 65109
Gene Symbol: UPF3B
UPF3B 		0.010 GeneticVariation disease BEFREE Loss-of-function mutations in UPF3B result in variable clinical presentations including intellectual disability (ID, syndromic and non-syndromic), autism, childhood onset schizophrenia and attention deficit hyperactivity disorder. 23821644 2013
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.010 GeneticVariation disease BEFREE Inconsistent with expectations, no significant associations were found between MTHFR C677T polymorphism and schizophrenia in children. 31302825 2019
Entrez Id: 2571
Gene Symbol: GAD1
GAD1 		0.020 Biomarker disease BEFREE In the present study, SNPs in and around the GAD1 gene, which encodes the protein GAD67, were tested on a rare, severely ill group of children and adolescents with childhood-onset schizophrenia (COS) (n=72), in a family-based association analysis. 15505639 2005
Entrez Id: 5740
Gene Symbol: PTGIS
PTGIS 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 5970
Gene Symbol: RELA
RELA 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 4232
Gene Symbol: MEST
MEST 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 342667
Gene Symbol: STAC2
STAC2 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 84630
Gene Symbol: TTBK1
TTBK1 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 339231
Gene Symbol: ARL16
ARL16 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 282809
Gene Symbol: POC1B
POC1B 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 8693
Gene Symbol: GALNT4
GALNT4 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 91662
Gene Symbol: NLRP12
NLRP12 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 124925
Gene Symbol: SEZ6
SEZ6 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 387509
Gene Symbol: GPR153
GPR153 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 341640
Gene Symbol: FREM2
FREM2 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 23024
Gene Symbol: PDZRN3
PDZRN3 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 9146
Gene Symbol: HGS
HGS 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016